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calculus science definition

Plural calculi calculi or calculuses
  1. The branch of mathematics that deals with limits and the differentiation and integration of functions of one or more variables. See more at calculus of variations, differential calculus, integral calculus.
  2. A solid mass, usually composed of inorganic material, formed in a cavity or tissue of the body. Calculi are most commonly found in the gallbladder, kidney, or urinary bladder. Also called stone.

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