leukemia science definition

Any of various acute or chronic neoplastic diseases of the bone marrow in which unrestrained proliferation of white blood cells occurs, usually accompanied by anemia, impaired blood clotting, and enlargement of the lymph nodes, liver, and spleen. Certain viruses, genetic defects, chemicals, and ionizing radiation, are associated with an increased risk of leukemia, which is classified according to the cellular maturity of the involved white blood cells.