The amount of an element, compound, or other substance that has the same number of basic particles as 12 grams of Carbon-12. The number of particles making up a mole is Avogadro's number. For elements and compounds, the mass of one mole, in grams, is roughly equal to the atomic or molecular weight of the substance. For example, carbon dioxide, CO2, has a molecular weight of 44; therefore, one mole of it weighs 44 grams.