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translocation science definition
- A chromosomal aberration in which a chromosomal segment changes position, usually moving from one chromosome to a different, nonhomologous chromosome. In one type of Down Syndrome, for example, translocation of a large segment of chromosome 21 to another chromosome results in an individual who has the genetic equivalent of three chromosomes 21 and thus has the phenotype of Down syndrome but who has a normal total number of chromosomes. A translocation within a given chromosome is called a shift.
- A chromosomal segment that is translocated.
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